TSKgel ODS-140HTP

TSKgel ODS-140HTP columns provide high resolution and short analysis time at moderate pressures for high throughput separations. The polylayer bonding chemistry of the 2.3 µm particle results in highly efficient and durable columns. The moderate pressure drop compared to sub 2 µm columns reduces the burden on the hardware, allowing the TSKgel ODS-140HTP columns to be used with either UHPLC or conventional HPLC systems.

For use in high throughput applications, including drug discovery, pharmacokinetics and peptide digest separations, TSKgel ODS-140HTP columns offer excellent peak shape for basic compounds.

P/N	Description	Particle Size (µm)	Housing Material	ID (mm)	Length (cm)	Price ($)
0021927	TSKgel ODS-140HTP	2.3	Stainless Steel	2.1	5	855	Inquire
0021928	TSKgel ODS-140HTP	2.3	Stainless Steel	2.1	10	881	Inquire

Product Attributes

Pore size (mean):	14 nm
Endcapped:	Yes
Particle Size:	2.3 µm
pH stability:	2.0 - 7.5
Functional group:	C18 (polymeric bonding chemistry)
% Carbon:	6

Structure:

Analysis of Six Cold and Sinus Drug Standards

Time (min)	Solvent B (%)	Flow (mL/min)
1.4	2.0	0.6
1.5	24.0	1.4
2.1		1.4
2.2		0.8
4.0	5.0	0.8
4.1	1.0	0.6

Columns:	TSKgel ODS-140HTP, 2.3 µm, 2.1 mm ID × 5 cm
Mobile phase:	A: H₂O with 0.15% TFA B: 100% ACN with 0.15% TFA
Gradient:	see table
Detection:	UV @ 215 nm
Temperature:	50 °C
Injection vol.:	10 µL
Sample:	1. maleate peak 2. phenylephrine 3. acetaminophen 4. doxylamine succinate 5. chlorpheniramine maleate 6. dextromethorphan HBr 7. diphenhydramine HCl

For additional applications, please see our applications database.

Durability of TSKgel ODS-140HTP Columns

Column:	TSKgel ODS-140HTP, 2.3 µm, 2.1 mm ID × 10 cm
Mobile phase:	H₂O/MeOH = 30/70
Flow rate:	0.2 mL/min
Detection:	UV @ 254 nm
Temperature:	25 °C
Injection vol.:	2 µL
Sample:	1. phenol 2. benzene 3. toluene 4. napthalene

Code #	Description	Literature Type
AN017	TSKgel ODS-140HTP, 2.3µm: Ultra High Performance Reversed Phase for High Throughput Analysis	Application Note
AN020	TSKgel ODS-140HTP, 2.3μm Columns for the Fast and Reliable Separation of Drugs Used in Cold and Sinus OTC Medicines	Application Note
AN022	High Throughput Reversed Phase HPLC Analysis of Caffeine using TSKgel ODS-140HTP and ODS-100V Columns	Application Note
AN070	Use of Reversed Phase and HILIC in the 2D-LC Separation of Cationic, Anionic, and Hydrotropic Surfactants	Application Note
DS1228	TSKgel ODS-140HTP Products	Operating Conditions and Specifications
IM01	TSKgel Column Instruction Manual	Instruction Manual
LCAT05A	TSKgel U/HPLC Columns 2019 Product Guide -- RPC Columns, Silica-Based	Product Catalog
PO15	TSKgel ODS-140HTP Columns	Product Overview
TP130	LC/MS Application of new 2.3 micron ODS Column in High-Throughput Pharmaceutical Analysis	Technical Presentation
TP142	The Separation of Popular Cold, Sinus, and Allergy Medications using TSKgel ODS-140HTP Columns	Technical Presentation
TP143	High Throughput Analysis of Caffeine and Other Food and Beverage Additives Present in Popular Soft Drinks using High Performance Reversed Phase HPLC	Technical Presentation
TP144	High Throughput Analysis of a Number of Common Drugs using a TSKgel ODS-140HTP, 2.3μm Column	Technical Presentation
TP146	High Throughput Analysis of a Number of Common Drugs using TSKgel ODS-140HTP Columns	Technical Presentation
TP147	Analysis of a Number of Common Drugs using TSKgel ODS-140HTP, 2.3μm High Throughput Reversed Phase Columns	Technical Presentation
TP150	High Throughput Separation of Hypertension Drug Standards by Reversed Phase Chromatography using TSKgel ODS-140HTP, 2.3µm Columns	Technical Presentation
TP153	High Throughput Analysis of Orlistat® Drug Standard and Corresponding Non-Prescription Over-The-Counter Drug alli® using TSKgel ODS-140HTP, 2.3μm Columns	Technical Presentation
TP154	Analysis of an Anti-Obesity OTC Drug alli® (orlistat) using a High Throughput Reversed Phase Column	Technical Presentation
TP200	Analytical Separation Of Oligonucleotides Using Strong Anion Exchange and C18 Reversed Phase Chromatography	Technical Presentation
TP201	Use of Reversed Phase and HILIC in the 2D-LC Separation of Cationic, Anionic, and Hydrotropic Surfactants	Technical Presentation