EcoSEC® HT GPC System


Demanding high temperature polymer analyses, such as for polyolefins, require a system that delivers results reliably, reproducibly, and produces these results in an easy to use, safe instrument. The EcoSEC® High Temperature GPC System incorporates the proven design and technology used in our ambient EcoSEC Elite® GPC System.

The dual pump system, dual flow RI detector, spacious column oven, total system temperature control, autosampler, sample prep station, safety features, and all-in-one design controlled by intuitive software combine to deliver exceptional performance.

The EcoSEC® High Temperature GPC System features:

  • Reliability
  • Reproducibility
  • Stability
  • Safety
  • All-in-one design
  • Ease of use

What is unique about the EcoSEC® High Temperature GPC System?


Click on the individual component links below for more detailed information.

Solvent Reservoir
Control Panel
Temperature Controlled Pumps
Column Oven
RI Detector
Purge Unit and Degasser
EcoSEC® HT Workstation Software
Column Switching Valve Option
Sample Prep System Option


Tosoh Bioscience can tailor a system to meet your application needs.

Does your analysis require additional detectors beyond RI?
The EcoSEC® High Temperature GPC System provides easy, effortless and temperature controlled connectivity when using multi-detector configurations. We offer external light scattering and viscometry detectors, as well as coupling options for FT-IR analysis.

Contact us for a quote!



Flow rate 0.1 to 2.0 mL/min in 0.1 mL/min steps
Accuracy ± 2%
Precision ± 0.2%
Max. pressure 15 MPa


Injection volume 10 to 500 µL (dependent on sample loop size)
Number of samples 24

Column Oven

Temperature range 40 °C to 220 °C
Capacity 7.8 mm ID × 30 cm × 8 columns

RI Detector

Type Bryce (dual flow type),Tungsten light source.
Cell volume 10µL
1.5 × 10-8RIU (ODCB: 1.0 mL/min, 145°C, response: 3 s)
Drift 3 × 10-7RIU/h (ODCB: 1.0 mL/min, 145 °C)


Dimensions 1,000 (W) × 500 (D) × 650 (H) mm

The EcoSEC® High Temperature GPC System Workstation Software offers unparalleled versatility and includes these features:

  • GPC-specific EcoSEC® High Temperature GPC System software to simplify system control and data handling
  • Controls up to 2 EcoSEC® High Temperature GPC Systems
  • Excellent data handling and report generation
  • Fully featured data handling system; analyze data from two detectors
  • Start and stop system automatically
  • One license for multiple locations

Software features include:

  1. Flow Diagram
  2. Method Templates
  3. Peak Editing
  4. Data Management
  5. Multiprocessing Function
  6. GPC Specific Quantitative Calculations
  7. Report Generation

TSKgel® polystyrene bulk calibration standards are used to calibrate GPC columns for subsequent analysis of unknown samples.  The standards range from 400 to 2.1 × 107 Da.


TSKgel® H series GPC columns are recommended for the analysis of organic-soluble polymers and are packed with spherical particles composed of polystyrene cross-linked with divinylbenzene (PS-DVB).  The TSKgel® HT columns are for high temperature applications (≤ 140 °C) while the TSKgel® HT2 columns are used in ultra-high temperature (up to 220 °C) applications.

The figure below demonstrates the performance stability of the TSKgel® GMHHR-H HT columns compared to other commercially available high temperature GPC columns during repetitive temperature changes. The TSKgel® HHR HT columns and two commercially available high temperature GPC columns were subjected to drastic changes in temperature by raising the temperature for 2 hours followed by lowering the temperature for two hours for a total of 60 cycles. The number of theoretical plates was shown to remain constant for the TSKgel® HHR HT columns and to decrease by 15% for the two commercially available high temperature GPC columns; thus revealing the superior performance stability of the TSKgel® HHR HT columns. 



Mobile phase:
Flow rate:

TSKgel® GMHHR-H HT2, 5 µm,
7.8 mm ID × 30 cm × 2
ODCB with 0.05% BHT
1.0 mL/min
RI (EcoSEC® High Temperature
GPC System)
40 to 145 °C