EcoSEC Elite® GPC System


The EcoSEC Elite® GPC System is a dedicated GPC instrument developed for fast polymer analysis. The all-in-one design concept delivers these benefits:

  • low dead volume for improved resolution and molar mass distribution accuracy
  • temperature controlled pumps for excellent flow rate precision regardless of changes in laboratory temperature
  • dual flow RI (refractive index) detection for unmatched baseline stability. 

Time and solvent can be saved using the EcoSEC Elite® GPC System with optional semi-micro columns due to the system’s low dead volume. The dead volume of the EcoSEC Elite® GPC System (<20 μL) is less than half the dead volume of conventional GPC systems. 


What sets an EcoSEC Elite® GPC System apart?


Click on the individual component links below for more detailed information.

EcoSEC Elite components

Column Switching Valve Option
Control Panel
RI Detector
UV Detector Option
Column Oven

Tosoh Bioscience can tailor a system to meet your application needs.

Does your analysis require additional detectors beyond RI and UV?
The EcoSEC Elite® GPC System provides easy and effortless connectivity when using multi-detector configurations. We offer external light scattering and viscometry detectors.

Contact us for a quote!



Flow rate 0.010 to 2.000 mL/min in 0.001 mL/min steps
Accuracy ± 2%
Precision ± 0.2%
Max. pressure 25 MPa or 3,500 psi
Safety features Liquid supply stops if pressure rised above the upper limit or drops below the lower limit, Plunger drive count monitoring, Pan for liquid leakage
Stroke volume 7.51 µL


Injection volume 1 to 1,500 µL in 1 µL increments
Number of samples 100, 2 mL injection vials
50, 2 mL injection vials with use of optional temperature controlled sample rack

Column Oven

Temperature range Off, 40 °C to 60 °C, in increments of 1 °C
Capacity 7.8 mm ID × 30 cm × 8 columns
Accuracy ± 0.5 °C
Precision ± 0.2 ºC, 0.4

RI Detector

Type Bryce (dual flow type), Red LED light source (λp: 630 to 670 nm)
Optics Deflection
Cell volume 2.5 µL
Cell pressure limit 0.5 MPa
Noise 2 × 10-9 RIU
Drift 0.8 × 10-7 RIU/h (THF, 1.0 mL/min)
Dynamic range ±2.5× 10-4 RIU
Temperature control Off, 40°C to 60°C, in increments of 1 °C
Analog out For connection to third party light scattering and viscometry detectors
Safety features Leak sensor and thermal fuse for circuit block

UV Detector (optional)

System Dual beam, single flow cell
Light source Deuterium lamp
Wavelength range 195 to 350 nm
Wavelength accuracy ± 2 nm
Bandwidth 8 nm
Range (FS) 0.5, 1, 2, 4 AU/1 V
Response 0.5, 1.0, 3.0 seconds
Drift < 3 × 10-AU/h (254 nm, air in cell, response: 1.0 s)
Noise < 1.5 × 10-5 AU (254 nm, air in cell, response: 1.0 s)
Flow cell volume 2 µL
Safety mechanism Liquid leakage sensor; lighting time monitoring


Dimensions 680 (W) × 500 (D) × 550 (H) mm = 2.2' × 1.6' × 1.8'
Weight 71 kg = 157 lbs
Dead volume < 20 µL


The EcoSEC Elite® GPC System Workstation Software offers unparalleled versatility and includes these features:

  • GPC-specific EcoSEC Elite® GPC System software to simplify system control and data handling
  • Controls up to 2 EcoSEC Elite® GPC Systems
  • Excellent data handling and report generation
  • Fully featured data handling system; analyze data from two detectors
  • Start and stop system automatically
  • One license for multiple locations

Software features include:

  1. Method Templates
  2. Peak Editing
  3. Data Management
  4. Multiprocessing Function
  5. GPC Specific Quantitative Calculations
  6. Report Generation
  7. Software Specifications


PStQuick polystyrene calibration standards contain pre-mixed quantities of polystyrene polymers in autosampler vials for the calibration of GPC columns. Addition of solvent is all that is required for easy preparation and analysis. 12 different kits containing polystyrene polymers of various molar masses are available. Of the 12 kits, 9 are individual kits, each containing 3 to 5 polystyrene polymers. The remaining 3 are composite kits containing 2 or 3 of the individual kits.


Tosoh introduced its first line of GPC columns in 1971. Ever since, Tosoh scientists have made important contributions to advances in polymer analysis by developing state-of-the-art GPC columns for the most demanding applications.

Semi-micro columns are the TSKgel® columns of choice for use with the EcoSEC Elite® GPC System. They are referred to as such since their dimensions are smaller than conventional columns in terms of internal diameter as well as in length: 4.6 mm or 6 mm ID × 15 cm vs. 7.8 mm ID × 30 cm.