TSKgel BioAssist DS columns are designed for the desalting and buffer exchange of proteins and polynucleotides at semi-preparative scale. Packed with 15 μm polyacrylamide beads in PEEK hardware, TSKgel BioAssist DS columns show excellent desalting performance. These columns can be operated in standard HPLC systems to quickly and efficiently reduce salt and/or buffer concentrations of collected protein or nucleic acid fractions.

The novel* hydrophilic highly cross-linked polyacrylamide beads exhibit superior mechanical strength compared with conventional hydrophilic polyacrylamide beads and cross-linked dextran beads. This increase in strength is what allows the use of the small spherical 15 μm beads.