TSKgel SuperHZ4000 columns are packed with rigid, porous, 3 μm polymer beads. These ultra-fine particles provide high resolution for the non-aqueous separation of solvent-soluble small molecules and oligomers less than 4 × 105 Da. The maximum operating temperature for the TSKgel SuperHZ4000 columns are 80 °C. The THF shipping solvent may be replaced by a limited number of organic solvents.
TSKgel SuperHZ4000 columns are ideal for high throughput, high efficiency GPC applications such as those encountered in combinatorial chemistry experiments. These columns feature ultra-low sample adsorption, i.e., the columns show true size exclusion behavior for most polymers.
TSKgel SuperHZ4000 column dimensions are 6 mm ID × 15 cm and 4.6 mm ID × 15 cm versus 7.8 mm ID × 30 cm for conventional GPC columns. The smaller column dimensions translate to a reduction of peak volume by a factor of 3.4 (6 mm ID) and a factor of 5.8 (4.6 mm ID) versus the same component eluting from a corresponding TSKgel G4000Hxl column. Thus, your HPLC system may require optimization of components that can give rise to extra-column band broadening, such as connecting tubing, injector, injection volume, detector cell volume, and detector time constant.