Dynamic Binding Capacity Comparision of AIEX Resins for BSA @ 100 cm/hr
![IEX_SuperQ_DEAE_QAE-650M_DBC_rev.png](https://separations.us.tosohbioscience.com/Image Library/TBL/Product Catalog/Process Media/Anion Exchange/IEX_SuperQ_DEAE_QAE-650M_DBC_rev.png)
Resins: |
binding capacity
(10% breakthrough) |
TOYOPEARL DEAE-650M |
40.1 g/L |
TOYOPEARL QAE-550C
|
81.3 g/L |
TOYOPEARL SuperQ-650M
|
128.8 g/L |
|
|
Benzyl Alcohol Removal
![IEX_SuperQ-650M-Fig6.png](https://separations.us.tosohbioscience.com/Image Library/TBL/Product Catalog/Process Media/Anion Exchange/IEX_SuperQ-650M-Fig6.png)
A 2% solution of benzyl alcohol in water has been identified as a suitable alternative to 20% ethanol as a preservative in resin storage solutions. A sample of TOYOPEARL SuperQ-650M resin was prepared by adding 100 mL of aqueous 2% benzyl alcohol to 100 mL of suction filtered resin. A 100 mL aliquot of DI water was added to the filtered resin and stirred to make a slurry. This resin/ DI water slurry was allowed to stand for 5 minutes and was then suction filtered to remove the supernatant. This procedure was repeated 14 more times, for a total of 15 washes.
Samples of the filtered supernatant from the TOYOPEARL SuperQ-650M resin was taken after the 5th, 10th, and 15th washes and analyzed for benzyl alcohol concentration. As demonstrated in the figure, a 2% benzyl alcohol solution can be removed from the TOYOPEARL SuperQ-650M resin by thorough washing with DI water.
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