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T00805

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Sensitive determination of omeprazole and its two metabolite in human plasma by high-perfomance liquid chromatography.

5-hydroxyomeprazole; omeprazole; omeprazole sulfone; I.S（lansoprazole）

 
Chromatographic conditions
Column:TSKgelODS-100Z 5µm（4.6×15）, P/N 21461, 4.6mm ×15cm
Mobile Phase:50mmol/L Na2HPO4（pH6.0）/acetonitrile/methanol＝65/30/5
Flow Rate:1.0mL/min（0-16min）、1.5mL/min（16-25min）
Detection: UV/VIS 302nm
Temperature:40°C
Injection Volume:10µL
Reference:Tosoh　Technical　Information
Title:Sensitive determination of omeprazole and its two metabolite in human plasma by high-perfomance liquid chromatography
Number:119