Tosoh Bioscience Introduces TSKgel SP-3PW (30), a Higher Capacity Resin for the
Purification of Insulin and other Therapeutic Peptides and Small Proteins

April  16,  2010 -

King of Prussia, PA  -  Tosoh Bioscience LLC, a provider of chromatographic solutions for biopurification, recently announced the introduction of a new line of TSKgel SP-3PW (30) resins for use in large scale purification of peptides and proteins. Packaging container volumes vary from 100mL up to 50 L.

The TSKgel SP-3PW (30) resin is manufactured with a new production technology which yields a narrower particle size distribution. The 250 Å pore of the particles is ideal for insulin and similarly sized molecules. The smaller pore size coupled with a higher ligand density account for the higher capacity over TSKgel 5PW resins.

The new polymer technology creates an additional selectivity tool for use by the developer for demanding separation problems. TSKgel SP-3PW (30) resins can be used for both polishing and intermediate purification process steps.

According to Al Jackewitz, marketing manager of process development resins at Tosoh Bioscience LLC, the new resin can be made in larger batches than the other TSKgel SP-5PW resins, and the new technology may be applied to other ligands in the near future.

The new resin is in inventory and now available for purchase.