Tosoh Bioscience Expands the SkillPak™ Series of Pre-packed Columns

New dimensions of SkillPak columns now available

King of Prussia, PA - Tosoh Bioscience LLC, a provider of chromatographic solutions for the separation and purification of biomolecules, announced today the introduction of 2.5 and 5.0 cm ID SkillPak pre-packed columns (SkillPak 50 and SkillPak 200). These process development columns are designed for the process development of monoclonal antibodies, antibody fragments, ADCs, oligonucleotides, and viruses.

SkillPak Pre-packed Columns

Pre-packed with TOYOPEARL® or TSKgel® process chromatography media, all SkillPak columns deliver high performance and offer scalability and convenience – giving customers greater flexibility to use process media from Tosoh. The new SkillPak 50 (2.5 cm ID × 10 cm L; ~50 mL) and SkillPak 200 (5.0 cm ID × 10 cm L; ~200 mL) allow seamless scale-up of chromatography processes after method development on 1 mL and 5 mL SkillPak pre-packed columns.

SkillPak columns packed with affinity, anion and cation exchange, hydrophobic interaction, and size exclusion chromatographic resins (respectively, AFC, AEX, CEX, HIC, and SEC) are available with short delivery times. Optimal performance is guaranteed with the columns, and they can be operated directly with commonly used low or medium pressure liquid chromatography systems. They are reproducibly packed, and the applied procedures take into account the varying compressibility of each resin. This provides an accurate representation of conditions found in full-scale columns.

SkillPak 50 and SkillPak 200 pre-packed columns are now available for sale in the Americas from Tosoh Bioscience LLC.


Tosoh Bioscience LLC provides liquid chromatography products to laboratories and manufacturing plants in the Americas. While the majority of our customers work in biotechnology and pharmaceutical companies, our U/HPLC columns and systems are essential tools for sample analysis in most industries. The LenS®3 Multi-Angle Light Scattering Detector offers a revolutionary approach for the measurement of molecular weight (MW) and radius of gyration (Rg) of synthetic polymers, polysaccharides, proteins, and biopolymers. Our all-in-one dedicated GPC system, the EcoSEC® GPC System, is predominantly used in the chemical and polymer industries while our EcoSEC High Temperature GPC System is ideal for the polyolefin and oil industries. In the field of biotechnology, our preparative chromatography resins play a critical role in the purification of proteins and nucleic acids for medical purposes.

The company is a subsidiary of Tosoh Corporation in Japan, the parent of the Tosoh Group, which comprises over 100 companies worldwide and a multiethnic workforce of over 13,600 people and generated net sales of ¥918.6 billion (US$8.2 billion at the average rate of ¥112.4 to the US dollar) in fiscal 2022, ended March 31, 2022. Tosoh’s Bioscience Division comprises products and solutions of both separation and purification and of clinical diagnostics serving customers worldwide.


Marketing Communications
Tosoh Bioscience LLC

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