Tosoh Bioscience and ProSep Announce Strategic Partnership to Advance Chromatography Solutions

Tosoh Bioscience, a leading provider of chromatographic solutions for biomolecule separation and purification, announced its strategic partnership with ProSep Ltd., a renowned name in advanced separation and purification equipment for selected industries. This collaboration is designed to refine and expand the focus of both companies in their respective core markets


King of Prussia, Pennsylvania – Tosoh Bioscience, a leading provider of chromatographic solutions for biomolecule separation and purification, announced its strategic partnership with ProSep Ltd., a renowned name in advanced separation and purification equipment for selected industries. This collaboration is designed to refine and expand the focus of both companies in their respective core markets.

A Legacy Continued with Phoenix System

Central to this partnership is the Octave system, initially developed by Semba Biosciences for small molecule and sugar applications. After Semba’s acquisition, Tosoh Bioscience has effectively leveraged this foundational technology to develop its advanced multi-column chromatography (MCC) systems, the Octave BIO and Octave PRO, specifically designed for the purification of biomolecules. These innovative systems underscore Tosoh Bioscience’s commitment to enhancing biomanufacturing productivity, offering process flexibility, and ensuring the highest product quality while reducing production costs.

However, the Octave system's inception was rooted in addressing the complex needs of small molecule and sugar purification. Since Semba’s acquisition, Tosoh Bioscience has seen continuous demand for the original Octave system, as it offers a unique solution for these specific industries. Therefore, the original Octave system will be commercialized under the new brand name Phoenix by ProSep Ltd., expanding its purification technology portfolio for small molecules.

Leadership Insights on Strategic Collaboration

Oli Davalos, Global Product Manager Growth Initiatives at Tosoh Bioscience and the driving force behind this partnership, shares, “In this exciting partnership with ProSep Ltd., we're entrusting a key piece of our legacy technology, the Phoenix system, into very capable hands. ProSep's expertise in small molecule purification is unparalleled, and this collaboration allows them to enhance their portfolio, offering state-of-the-art solutions in their specialized domain.”

Brian Harbrecht, Manager of MCC Chromatography Research and Design Engineering at Tosoh Bioscience, who played a pivotal role in the development of the Octave technology, adds, “The Phoenix system is a testament to the enduring legacy of the Octave technology. Our collaboration with ProSep Ltd. ensures that this technology continues to evolve and meet the dynamic needs of the industry.”

Strategic Vision and Future Outlook

Dr. Romain Dabre, Director of Global Product Management at Tosoh Bioscience, explains the strategic decision, "Entrusting the Phoenix system to ProSep Ltd. is a strategic step in Tosoh Bioscience’s long-term vision. This move enables us to dedicate full attention and resources to the Octave BIO and PRO systems. Our strategy is focused on strengthening our core competencies and sustaining our leadership in providing advanced chromatographic solutions for the biopharmaceutical industry."

Luke Burke, President of ProSep, shares his vision for Phoenix, “ProSep Ltd is thrilled to assume responsibility for the Phoenix system, recognizing its significance as a valuable Research and Development tool. We are poised to leverage our expertise to transition its innovations into large-scale production seamlessly. Aligning with ProSep's reputation for designing cutting-edge Separation, Ion Exchange, and Filtration technologies. Both ProSep and Tosoh’s commitment to excellence and innovation ensures that the Phoenix system will not only meet but exceed the expectations of the industry.”

Tosoh Bioscience LLC

Tosoh Bioscience LLC provides liquid chromatography products to laboratories and manufacturing plants in the Americas. While most of our customers work in biotechnology and pharmaceutical companies, our U/HPLC columns and instruments are essential tools for sample analysis in most industries. In the field of biotechnology, our preparative chromatography resins and MCC instruments play a critical role in the purification of proteins and nucleic acids for medical purposes.

The company is a subsidiary of Tosoh Corporation in Japan, the parent of the Tosoh Group, which comprises over 100 companies worldwide and a multiethnic workforce of over 14000 people and generated net sales of ¥ 1064.4billion (US$7.9 billion at the average rate of ¥135.5 to the US dollar) in fiscal 2023, ended March 31, 2023. Tosoh’s Bioscience Division comprises products and solutions for both separation and purification and clinical diagnostics serving customers worldwide.


ProSep Ltd.

ProSep Ltd is a leading international provider of advanced separation and purification equipment since 1991. As a foremost engineering firm in the industry, our products and services are built upon the highest standards, integrity and innovation. Our relationships with our clients mean everything to us, in which, we strive to keep providing the best technology and service on a worldwide scale


Tosoh Bioscience is a registered trademark of Tosoh Corporation.
Octave is a trademark of Tosoh Bioscience LLC.
Phoenix is filed trademark of ProSep Ltd.


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