The EcoSEC® GPC system contains two pumps, a sample pump to deliver sample and solvent through the column, the other pump is designed to flow solvent (via a reference column) to the reference cell of the RI detector. By installing an optional column switching valve and replacing the reference column with another analytical column, an analysis can be performed on column 1, while equilibrating column 2. After switching the valve, column 2 becomes the measurement column, while column 1 will be in the flow path to the reference side of the RI detector flow cell
Since the column switching valve changes column sets while the oven door remains closed and switches to an already equilibrated column set, a stable baseline is rapidly established.
The optional column switching valve shortens the time needed to reach a stable baseline after switching columns. Applications include switching between a low and high MM linear column and analyzing the same sample on two different column types using a single solvent.
A: Flow path with column 1 as the analytical column B: Flow path with column 2 as the analytical column
