Products
Multi Column Chromatography
The Octave™ BIO is the most comprehensive and versatile multi-column chromatography (MCC) system for process development and proof of concept. Leveraging established Octave MCC technology from other industries and tailoring it for bioprocess use cases, these systems are designed to intensify your existing biologic purification process. The unique modular design will fit your requirements and unlock the resin savings, buffer savings, and other tangible benefits that MCC can provide.
• Benchtop system based on rugged, reliable, patented Octave technology
• Specifically designed for bioseparations
• Flow rates ranging from 1 mL/min to 300 mL/min
• Up to eight columns
• Six pumps, six inlets, six outlets
• User-replaceable valve block available in three channel diameters
• Integrated UV, conductivity, and pH sensors (4 of each)
• Gradient capabilities and single column mode with sample injector
• Complete data recording and analysis
• Includes PROComposer™ Method Creator and Method Wizard applications
• Powerful, user-friendly, BIOController™ control system
• Dedicated SkillPak BIO pre-packed columns for MCC applications are available.
The Octave BIO is available in 4 configurations:
0041100 - Octave BIO Benchtop System 12 mL/min
0041101 - Octave BIO Benchtop System 36 mL/min
0041102 - Octave BIO Benchtop System 100 mL/min
0041103 - Octave BIO Benchtop System 300 mL/min |
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Specifications
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| Dimensions (W / D / H) |
137 x 51 x 98 cm; bench top |
| Weight |
171 kg |
| Power requirements |
100–120/220–240 VAC, 50/60 Hz |
| Valve pressure |
At least 2 bar above process pressure |
| Flow rate range |
up to 40 mL/min (1 mm valve block)
up to 100 mL/min (1.6 mm valve block)
up to 300 mL/min (2.4 mm valve block) |
| Inlets |
6 |
| Outlets |
6 |
| Columns |
1-8 |
| Maximum operating pressure |
270 psi (18.6 bar) |
| UV sensors |
4, LED, dual wavelengths |
| Conductivity sensors |
4, range 0-200 mS/cm |
| pH sensors |
4, range pH 0-14 |
| Modes |
Step, batch, gradient, parallel, SMB |
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